Nucleosides and Analogues
Apexbio Technology LLC Adenosine 5-triphosphate 34369-07-8 500mg
Adenosine 5-triphosphate (ATP CAS 34369-07-8) also known as ATP disodium salt hydrate is a nucleotide central to cellular energy transfer It functions as the primary intracellular energy carrier undergoing hydrolysis to release energy required for numerous biochemical processes including muscle contraction signal transduction and biosynthetic reactions ATP also serves as a substrate for kinases in phosphorylation events and plays a regulatory role in purinergic signaling pathways In biomedical research ATP is widely used to study cellular metabolism enzyme activities and receptor-mediated responses
Medchemexpress LLC Guanosine 5'-triphosphate trisodium salt hydrate | 207300-85-4 | 95.0% | 100 MG
Guanosine 5'-triphosphate trisodium salt hydrate is an activator of the signal transducing G proteins and serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
- Activator of signal transducing G proteins
- Energy-rich precursor in DNA and RNA biosynthesis
- For research use only
Medchemexpress LLC Guanosine 5'-diphosphate sodium | 43139-22-6 | 99.88% | 465.18 | 50 MG
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates the adenosine 5'-triphosphate-sensitive K+ channel. It acts as an iron mobilizer by forming a complex with hepcidin, inhibiting the hepcidin-ferroportin (FPN) interaction, and modulating the IL-6/stat-3 pathway. It has been shown to ameliorate Turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4 and can be used in AI research.
- Activates adenosine 5'-triphosphate-sensitive K+ channel
- Acts as an iron mobilizer by forming a complex with hepcidin
- Inhibits hepcidin-ferroportin (FPN) interaction
- Modulates the IL-6/stat-3 pathway
- Ameliorates turpentine-induced anemia of inflammation (AI) in mice when combined with FeSO4
- Suitable for AI research
Apexbio Technology LLC 2'-O-Methyl-2-Amino-ATP 100ul (100 mM)
2p-O-Methyl-2-Amino-ATP is a modified nucleoside triphosphate incorporating methylation at the ribose 2 -hydroxyl group and an amino substitution at the 2 position of the adenine base It is designed to alter nucleotide biochemical properties impacting RNA stability and structure upon enzymatic incorporation In in vitro transcription assays 2p-O-Methyl-2-Amino-ATP demonstrates an ability to increase RNA resistance to exonuclease-mediated degradation and induce altered RNA secondary structures Based on these properties 2p-O-Methyl-2-Amino-ATP holds research potential in studies of RNA folding dynamics stability assays RNA-protein interactions and analyses involving chemically modified RNA in biomedical research
Medchemexpress LLC 1H-Purine-2,6-dione, 8-[[(6-chloro-2-fluoro-3-methoxyphenyl)methyl]amino]-1-ethyl-3,7-dihydr- | 2550400-52-5 | 714810 | 98.3% | 395.82 | 25 MG
Adenosine receptor inhibitor 1 is a potent and selective adenosine receptor (AR) inhibitor. It demonstrates antinociceptive, anti-inflammatory, and peripheral analgesic effects, with potential applications in cancer and neurodegenerative disease research.
- Potent and selective adenosine receptor (AR) inhibitor.
- Exhibits antinociceptive activity.
- Shows anti-inflammatory effect.
- Possesses peripheral analgesic effect.
- Suitable for research into cancer and neurodegenerative diseases.
- Provided as a white to off-white solid.
- Purity of 98.3%.
Cambridge Isotope Laboratories DL-2-Hydroxyglutaric acid disodium salt (unlabeled) 0 01 g
DL-2-Hydroxyglutaric acid disodium salt (unlabeled) 0 01 g
Medchemexpress LLC Adenosine 5'-diphosphate | 58-64-0 | 99.5% | 427.20 | 25MG
Adenosine 5'-diphosphate | 58-64-0 | 99.5% | 427.20 | 25MG
Medchemexpress LLC Adenosine dialdehyde | 34240-05-6 | MFCD00056960 | 99.0% | 265.23 g/mol | C10H11N5O4 | 10MG
Adenosine dialdehyde is a purine nucleoside analogue that acts as a potent inhibitor of S-adenosylhomocysteine hydrolase (SAHH). It is used as a biochemical research reagent to investigate methylation pathways and methyltransferase activity, and is supplied in solid milligram quantities and as a 10 mM solution in DMSO for convenient assay preparation.
- Potent SAHH inhibitor for methylation pathway studies.
- Supplied in both solid and ready-to-use solution formats.
- High stated purity for analytical and research applications.
- Compatible with enzyme inhibition assays and cellular studies.
- Provided with datasheet, certificate of analysis, and safety data sheet for compliance.
Apexbio Technology LLC 2'-O-Methyl-ATP(Synonyms: 2'-O-Methyladenosine 5'-triphosphate, 2'-OMe-ATP, ATP 2'-O-Methyl analog), 50ul (100 mM).
2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
Medchemexpress LLC Acyclovir triphosphate sodium | 221119-43-3 | 99.7% | C8H14N5O12P3.xNa | 25 MG
Acyclovir triphosphate sodium (AcycloGTP sodium) is a derivative of Acyclovir that functions as an inhibitor of viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). This compound is also recognized as an inhibitor of HIV-1 reverse transcriptase, ultimately leading to the termination of viral DNA synthesis. It is intended for research use only.
- Competitively inhibits viral DNA polymerase.
- Acts as an analog to deoxyguanosine triphosphate (dGTP).
- Inhibits HIV-1 reverse transcriptase.
- Causes termination of viral DNA synthesis.
- Available for research purposes.
Medchemexpress LLC Guanosine 5'-triphosphate (trisodium salt) | 36051-31-7 | 95.0% | 50 MG
Guanosine 5'-triphosphate (trisodium salt) is a G protein signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. It can promote myogenic cell differentiation and induce human myogenic precursor cells to release exosomes. This product is for research use only and holds promise for research in biosynthesis and skeletal muscle regeneration.
- Acts as a G protein signaling activator
- Functions as a high-energy precursor in the biosynthesis of DNA and RNA nucleotide units
- Promotes myogenic cell differentiation by upregulating miRNA and myogenic regulatory factor expression
- Induces human myogenic precursor cells to release exosomes containing guanosine molecules
Cambridge Isotope Laboratories Guanosine phosphoramidite (U-13C10 98% U-15N5 98%) CP 95% 10 mg
Guanosine phosphoramidite (U-13C10 98% U-15N5 98%) CP 95% 10 mg
Medchemexpress LLC Cytarabine triphosph 25mg | 1179343-17-9 | 25 MG
Cytarabine triphosphate trisodium is the trisodium salt of cytarabine triphosphate and is used as a research reagent to study DNA synthesis inhibition and nucleoside metabolism.
- Trisodium salt form supplied as a solution.
- Pack size 25 mg, prepared as 100 mM x 500 μL in water for the 25 mg vial.
- Molecular formula C9H13N3Na3O14P3 and molecular weight 549.10 g/mol.
- Purity approximately 96.8%.
- Storage: solution at -20°C; prepared stock solution stability: -80°C for 6 months, -20°C for 1 month.
- Used as the active metabolite Ara-CTP in biochemical and cell-based assays targeting DNA synthesis.
Medchemexpress LLC Allopurinol riboside | 16220-07-8 | MFCD00057096 | 99.1% | 268.23 | C10H12N4O5 | 1 ML
Allopurinol riboside is a ribonucleoside metabolite of allopurinol reported to exhibit antiparasitic activity. It is provided for research applications as a characterized chemical with specified composition and storage recommendations.